San Francisco 49ers @ Arizona Cardinals: Jan 10, 2027

Updated
Week 18
San Francisco 49ers49ers
6-1 · Away
1:00 PM ET
Scheduled
Sunday, January 10, 2027
Arizona CardinalsCardinals
2-5 · Home

49ers vs Cardinals kicks off at 1:00 PM ET (10:00 AM PT) on Sunday, January 10, 2027 at State Farm Stadium, Glendale.

How to Watch 49ers vs Cardinals: Time, TV & Stream

Date & time
Sunday, January 10, 20271:00 PM ET / 10:00 AM PT
Watch on
TV not announced yet
Stream
NFL Sunday TicketOut of market; local channels in both markets
Stadium
State Farm StadiumGlendale
Week
NFL Week 18All Week 18 games

Outside the US: NFL Game Pass on DAZN.

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49ers vs Cardinals Preview

The 49ers (6-1) are leading the NFC West, the No. 2 seed in the NFC. The Cardinals (2-5) are No. 14 in the NFC, outside the top seven.

The 49ers score 28.1 points a game and allow 19.9; the Cardinals score 20.3 and allow 29.7. The 49ers are 2-1 away from home, and the Cardinals are 0-3 at home. As an NFC West game, it also counts in the division record, the second tiebreaker for the division title. Their last meeting, on Sep 27, 2026, ended Cardinals @ 49ers 30-36.

49ers vs Cardinals: Tale of the Tape

49ersNFC West division gameCardinals
6-1
Record
2-5
NFC #2
Playoff seed
NFC #14
28.1
Points per game
20.3
19.9
Points allowed
29.7
+8.3
Point differential
-9.4
2-1
Road / home record
0-3
3-0
Division record
1-2
L1
Streak
L1
7 days
Rest
7 days

Going into the game, from every 2026 regular-season final. Seeds follow the NFL format (division leaders 1-4, Wild Cards 5-7); equal records are split with the NFL tiebreakers.

Injury Report

PlayerTeamPosStatusInjurySince
Alfred Collins49ersDLInjured ReserveSep 10, 2026
Andrew Farmer II49ersDLInjured ReserveJul 30, 2026
Austen Pleasants49ersOLInjured ReserveSep 7, 2026
Brandon Aiyuk49ersWRNon Football InjuryOct 27, 2026
C.J. West49ersDTInjured ReserveSep 23, 2026
Christian Kirk49ersWRQuestionableCalfOct 23, 2026
Darrick Forrest49ersSAFInjured ReserveMay 28, 2026
De'Zhaun Stribling49ersWRInjured ReserveSep 16, 2026
Deebo Samuel Sr.49ersWROutHamstringOct 23, 2026
Demarcus Robinson49ersWRInjured ReserveSep 26, 2026
Garret Wallow49ersLBOutHamstringOct 23, 2026
Isaac Guerendo49ersRBPhysically Unable To PerformJul 25, 2026
Jake Tonges49ersTEInjured ReserveSep 16, 2026
Luke Gifford49ersLBOutGroinOct 23, 2026
Marques Sigle49ersSAFOutAnkleOct 23, 2026
Mikail Kamara49ersDLInjured ReserveAug 3, 2026
Mike Evans49ersWROutRibs, AchillesOct 23, 2026
Nate Hobbs49ersCBInjured ReserveSep 1, 2026
Nick Bosa49ersDLOutKnee, CalfOct 23, 2026
Nick Martin49ersLBInjured ReserveSep 1, 2026
Nick Zakelj49ersOLInjured ReserveAug 31, 2026
Ricky Pearsall49ersWRInjured ReserveAug 1, 2026
Sam Okuayinonu49ersDLInjured ReserveSep 5, 2026
Siran Neal49ersDBQuestionableKneeOct 23, 2026
Upton Stout49ersCBQuestionableShoulderOct 23, 2026
Andrew WingardCardinalsSAFOutKneeOct 23, 2026
Budda BakerCardinalsSAFQuestionableGroin, IllnessOct 23, 2026
Carson BeckCardinalsQBQuestionableBackOct 23, 2026
Chase BisontisCardinalsOLInjured ReserveAug 15, 2026
Darius RobinsonCardinalsDLQuestionableBackOct 23, 2026
Hunter LongCardinalsTEInjured ReserveOct 6, 2026
Isaiah AdamsCardinalsOLInjured ReserveOct 10, 2026
James ConnerCardinalsRBInjured ReserveAug 30, 2026
Jameson GeersCardinalsTEInjured ReserveAug 15, 2026
Jeremiyah LoveCardinalsRBOutAnkleOct 23, 2026
Joey BlountCardinalsSAFInjured ReserveAug 8, 2026
Jon Gaines IICardinalsOLOutKnee, AnkleOct 23, 2026
Kaleb ProctorCardinalsDLInjured ReserveJul 22, 2026
Max MeltonCardinalsCBQuestionableKneeOct 23, 2026
Paris Johnson Jr.CardinalsOLInjured ReserveOct 6, 2026
Tip ReimanCardinalsTEPhysically Unable To PerformJul 23, 2026
Trey BensonCardinalsRBInjured ReserveAug 26, 2026
Walter Nolen IIICardinalsDLOutAnkleOct 23, 2026
Will JohnsonCardinalsCBInjured ReserveSep 23, 2026
Zach CarterCardinalsDLInjured ReserveAug 31, 2026

Status as of 11:01 AM ET, Oct 27. Teams can change a player's status up to kickoff; check team announcements before the game.

Playoff Picture

NFC

SeedTeamW-LStatus
1Vikings6-0NFC North leader
249ers6-1NFC West leader
3Giants4-2-1NFC East leader
4Panthers3-3NFC South leader
12Buccaneers2-5Out
13Saints2-5Out
14Cardinals2-5Out
15Eagles2-5Out
16Commanders1-4-1Out

The seeds around both teams if the season ended today.

49ers vs Cardinals Head-to-Head

2026 season series49ers 1-0
2025 season series49ers 2-0

49ers last 5

Cardinals last 5

Previous meetings

49ers vs Cardinals Key Players

49ers logo49ers

Cardinals logoCardinals

Season leaders, regular season.

More NFL Games on Jan 10, 2027

This 49ers vs Cardinals page updates on its own: live score during the game, box score and recap minutes after the final whistle.

49ers vs Cardinals FAQs

What time does 49ers vs Cardinals start?

The San Francisco 49ers play the Arizona Cardinals on Sunday, January 10, 2027 at State Farm Stadium in Glendale. Kickoff is 1:00 PM ET (10:00 AM PT).

What are the 49ers and Cardinals records?

Going into this game the 49ers were 6-1 and the Cardinals were 2-5 this season.

Where do the 49ers and Cardinals stand in the playoff race?

The 49ers (6-1) are leading the NFC West, the No. 2 seed in the NFC. The Cardinals (2-5) are No. 14 in the NFC, outside the top seven. Seven teams per conference make the playoffs: four division winners and three Wild Cards.

Is 49ers vs Cardinals a division game?

Yes. Both teams play in the NFC West, so the result counts in the division record, the second tiebreaker for the division title after head-to-head. Division rivals meet twice a season.

Who is injured for 49ers vs Cardinals?

As of 11:01 AM ET, Oct 27: Alfred Collins (49ers, injured reserve); Andrew Farmer II (49ers, injured reserve); Austen Pleasants (49ers, injured reserve); Brandon Aiyuk (49ers, non football injury); C.J. West (49ers, injured reserve); Christian Kirk (49ers, questionable, calf).

Who leads the 49ers vs Cardinals season series?

The 49ers lead the regular-season series 1-0 this season.

Who won the last 49ers vs Cardinals game?

The 49ers beat the Cardinals 36-30 on Sep 27, 2026 at home.

Where is 49ers vs Cardinals being played?

At State Farm Stadium in Glendale, the home stadium of the Arizona Cardinals.