New Orleans Saints @ Buffalo Bills: Sep 28, 2025

Updated
Regular Season
New Orleans SaintsSaints
0-4 · Away
19–31
Final
Sunday, September 28, 2025
Buffalo BillsBills
4-0 · Home

Saints vs Bills final: the Buffalo Bills beat the New Orleans Saints 31-19 on September 28, 2025 at Highmark Stadium, Buffalo.

Score by Quarter

TeamQ1Q2Q3Q4T
Saints736319
Bills14071031

Saints vs Bills Recap

The Bills did the damage in the 1st quarter, winning that period by 7.

After the game, the Saints are 0-4 and the Bills are 4-0.

Saints vs Bills Game Info

Date & time
Sunday, September 28, 20251:00 PM ET / 10:00 AM PT
Stadium
Highmark StadiumBuffalo
Season
2025 NFL SeasonRegular season

Saints vs Bills: Tale of the Tape

SaintsNFC vs AFCBills
0-3
Record
3-0
NFC #15
Playoff seed
AFC #3
15.7
Points per game
34.0
30.0
Points allowed
23.7
-14.3
Point differential
+10.3
0-1
Road / home record
2-0
0-0
Division record
2-0
L3
Streak
W3
7 days
Rest
10 days

Before this game, from every 2025 regular-season final. Seeds follow the NFL format (division leaders 1-4, Wild Cards 5-7); equal records are split with the NFL tiebreakers.

Recent Form & Head-to-Head
2025 season seriesFirst meeting this season

Saints last 5

Bills last 5

More NFL Games on Sep 28, 2025

That covers Saints vs Bills: score, leaders and box score above. Next: Saints host the Browns Nov 8; Bills host the Ravens Nov 1.

Saints vs Bills FAQs

Who won Saints vs Bills on Sep 28, 2025?

The Buffalo Bills beat the New Orleans Saints 31-19 on Sunday, September 28, 2025 at Highmark Stadium in Buffalo.

What are the Saints and Bills records?

After this game the Saints were 0-4 and the Bills were 4-0 this season.

Where was Saints vs Bills played?

At Highmark Stadium in Buffalo, the home stadium of the Buffalo Bills.

What was the score by quarter in Saints vs Bills?

Saints-Bills: Q1 7-14, Q2 3-0, Q3 6-7, Q4 3-10.

What is next for the Saints and Bills?

Saints host the Browns on Sunday, November 8 at 1:00 PM ET; Bills host the Ravens on Sunday, November 1 at 1:00 PM ET.