49ers20
Bengals35
Dolphins28
Jets25
Broncos30
Cardinals16
SeahawksJacksonville Jaguars @ San Francisco 49ers: Sep 28, 2025
Jaguars vs 49ers final: the Jacksonville Jaguars beat the San Francisco 49ers 26-21 on September 28, 2025 at Levi's Stadium, Santa Clara.
Score by Quarter
| Team | Q1 | Q2 | Q3 | Q4 | T |
|---|---|---|---|---|---|
| Jaguars | 0 | 17 | 9 | 0 | 26 |
| 49ers | 3 | 3 | 8 | 7 | 21 |
Jaguars vs 49ers Recap
The Jaguars did the damage in the 2nd quarter, winning that period by 14.
After the game, the Jaguars are 3-1 and the 49ers are 3-1.
Jaguars vs 49ers Game Info
- Date & time
- Sunday, September 28, 20254:05 PM ET / 1:05 PM PT
- Stadium
- Levi's StadiumSanta Clara
- Season
- 2025 NFL SeasonRegular season
Jaguars vs 49ers: Tale of the Tape
- 2-1
- Record
- 3-0
- AFC #6
- Playoff seed
- NFC #2
- 23.3
- Points per game
- 19.7
- 17.0
- Points allowed
- 16.3
- +6.3
- Point differential
- +3.3
- 0-1
- Road / home record
- 1-0
- 1-0
- Division record
- 2-0
- W1
- Streak
- W3
- 7 days
- Rest
- 7 days
Before this game, from every 2025 regular-season final. Seeds follow the NFL format (division leaders 1-4, Wild Cards 5-7); equal records are split with the NFL tiebreakers.
Recent Form & Head-to-Head
Jaguars last 5
- W vs Texans 17-10 Sep 21, 2025
- L @ Bengals 27-31 Sep 14, 2025
- W vs Panthers 26-10 Sep 7, 2025
49ers last 5
- W vs Cardinals 16-15 Sep 21, 2025
- W @ Saints 26-21 Sep 14, 2025
- W @ Seahawks 17-13 Sep 7, 2025
More NFL Games on Sep 28, 2025
- Final
Minnesota Vikings6-021
Pittsburgh Steelers5-224 - Final
Los Angeles Chargers0-618
New York Giants4-221 - Final
New Orleans Saints2-519
Buffalo Bills5-131 - Final
Tennessee Titans1-60
Houston Texans2-526 - Final
Philadelphia Eagles2-431
Tampa Bay Buccaneers2-525 - Final
Carolina Panthers3-313
New England Patriots4-342 - Final
Cleveland Browns5-210
Detroit Lions4-234 - Final
Atlanta Falcons3-434 - Final
Indianapolis Colts2-520
Los Angeles Rams3-427 - Final
Baltimore Ravens4-320
Kansas City Chiefs5-037 - Final
Chicago Bears5-225
Las Vegas Raiders3-424 - Final
Green Bay Packers4-340
Dallas Cowboys2-440
That covers Jaguars vs 49ers: score, leaders and box score above. Next: Jaguars host the Colts Nov 1; 49ers host the Raiders Nov 8.
Jaguars vs 49ers FAQs
Who won Jaguars vs 49ers on Sep 28, 2025?
The Jacksonville Jaguars beat the San Francisco 49ers 26-21 on Sunday, September 28, 2025 at Levi's Stadium in Santa Clara.
What are the Jaguars and 49ers records?
After this game the Jaguars were 3-1 and the 49ers were 3-1 this season.
Where was Jaguars vs 49ers played?
At Levi's Stadium in Santa Clara, the home stadium of the San Francisco 49ers.
What was the score by quarter in Jaguars vs 49ers?
Jaguars-49ers: Q1 0-3, Q2 17-3, Q3 9-8, Q4 0-7.
What is next for the Jaguars and 49ers?
Jaguars host the Colts on Sunday, November 1 at 1:00 PM ET; 49ers host the Raiders on Sunday, November 8 at 4:05 PM ET.